Nicolas Perez-Mora
Svenson Medical, Spain
Title: Acute telogen effluvium in 503 female patients: The values of the effluvium triggering cause to predict female androgenetic alopecia association
Biography
Biography: Nicolas Perez-Mora
Abstract
Acute telogen effluvium (ATE) is often associated with Female Androgenetic Alopecia (FAA) but predictive factors of ATE - FAA association, and clinical factors or therapies which may influence the progression of ATE to Chronic Telogen Effluvium (CTE) have not been reported yet. We have retrospectively analyzed 503 ATE patients with a minimum 1-year follow-up. Demographic and clinical variables considered were: age, year when ATE diagnosis was made, region where patient was located, different oral treatment modalities, and Minoxidil topical therapy. Triggering causes were classified as follows: (1) Seasonal hair loss, (2) Severe Diet, (3) Postpartum, (4) Iron deficiency, (5) Psychoemotional stress, (6) Thyroid dysfunction, (7) Medication intake or withdrawal, (8) Antineoplastic therapies and/or major surgery, (9) More than one of the above mentioned. Chronic telogen effluvium (CTE) diagnosis was established when ATE lasted longer than 1 year. FAA diagnosis was always established by the patient’s physician. Univariate analysis and a binary logistic regression model were used to identify independent predictive factors of ATE – FAA association and CTE progression. Then, we have identified predictive factors of ATE – FAA association. Conclusions: Triggering Cause is an independent predictive factor of ATE-FFA Association. Triggering causes with higher risk of concurrent FAA are: severe diet, iron deficiency and thyroid dysfunction. Patients suffering ATE may benefit from different therapeutic approaches (depending on which is the triggering cause) to prevent or treat their association with FAA. Minoxidil use shows a trend to lower the percentage of progression to CTE.
